Pesquisa | BVS Violência e Saúde

1.

The cycling and aging mouse female reproductive tract at single-cell resolution.

Winkler, Ivana; Tolkachov, Alexander; Lammers, Fritjof; Lacour, Perrine; Daugelaite, Klaudija; Schneider, Nina; Koch, Marie-Luise; Panten, Jasper; Grünschläger, Florian; Poth, Tanja; Ávila, Bianca Machado de; Schneider, Augusto; Haas, Simon; Odom, Duncan T; Gonçalves, Ângela.

Cell ; 187(4): 981-998.e25, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38325365

2.

Unwinding Limb Development.

Villar, Diego; Odom, Duncan T.

Cell ; 167(3): 598-600, 2016 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-27768881

3.

Enhancer evolution across 20 mammalian species.

Villar, Diego; Berthelot, Camille; Aldridge, Sarah; Rayner, Tim F; Lukk, Margus; Pignatelli, Miguel; Park, Thomas J; Deaville, Robert; Erichsen, Jonathan T; Jasinska, Anna J; Turner, James M A; Bertelsen, Mads F; Murchison, Elizabeth P; Flicek, Paul; Odom, Duncan T.

Cell ; 160(3): 554-66, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25635462

4.

CTCF and cohesin: linking gene regulatory elements with their targets.

Merkenschlager, Matthias; Odom, Duncan T.

Cell ; 152(6): 1285-97, 2013 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-23498937

5.

Cooperativity and rapid evolution of cobound transcription factors in closely related mammals.

Stefflova, Klara; Thybert, David; Wilson, Michael D; Streeter, Ian; Aleksic, Jelena; Karagianni, Panagiota; Brazma, Alvis; Adams, David J; Talianidis, Iannis; Marioni, John C; Flicek, Paul; Odom, Duncan T.

Cell ; 154(3): 530-40, 2013 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-23911320

6.

Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages.

Schmidt, Dominic; Schwalie, Petra C; Wilson, Michael D; Ballester, Benoit; Gonçalves, Angela; Kutter, Claudia; Brown, Gordon D; Marshall, Aileen; Flicek, Paul; Odom, Duncan T.

Cell ; 148(1-2): 335-48, 2012 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-22244452

7.

DNA lesion bypass and the stochastic dynamics of transcription-coupled repair.

Nicholson, Michael D; Anderson, Craig J; Odom, Duncan T; Aitken, Sarah J; Taylor, Martin S.

Proc Natl Acad Sci U S A ; 121(20): e2403871121, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38717857

8.

Pervasive lesion segregation shapes cancer genome evolution.

Aitken, Sarah J; Anderson, Craig J; Connor, Frances; Pich, Oriol; Sundaram, Vasavi; Feig, Christine; Rayner, Tim F; Lukk, Margus; Aitken, Stuart; Luft, Juliet; Kentepozidou, Elissavet; Arnedo-Pac, Claudia; Beentjes, Sjoerd V; Davies, Susan E; Drews, Ruben M; Ewing, Ailith; Kaiser, Vera B; Khamseh, Ava; López-Arribillaga, Erika; Redmond, Aisling M; Santoyo-Lopez, Javier; Sentís, Inés; Talmane, Lana; Yates, Andrew D; Semple, Colin A; López-Bigas, Núria; Flicek, Paul; Odom, Duncan T; Taylor, Martin S.

Nature ; 583(7815): 265-270, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32581361

9.

Polyploidisation pleiotropically buffers ageing in hepatocytes.

Yin, Kelvin; Büttner, Maren; Deligiannis, Ioannis K; Strzelecki, Mateusz; Zhang, Liwei; Talavera-López, Carlos; Theis, Fabian; Odom, Duncan T; Martinez-Jimenez, Celia P.

J Hepatol ; 2024 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-38583492

10.

Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.

Thybert, David; Roller, Masa; Navarro, Fábio C P; Fiddes, Ian; Streeter, Ian; Feig, Christine; Martin-Galvez, David; Kolmogorov, Mikhail; Janousek, Václav; Akanni, Wasiu; Aken, Bronwen; Aldridge, Sarah; Chakrapani, Varshith; Chow, William; Clarke, Laura; Cummins, Carla; Doran, Anthony; Dunn, Matthew; Goodstadt, Leo; Howe, Kerstin; Howell, Matthew; Josselin, Ambre-Aurore; Karn, Robert C; Laukaitis, Christina M; Jingtao, Lilue; Martin, Fergal; Muffato, Matthieu; Nachtweide, Stefanie; Quail, Michael A; Sisu, Cristina; Stanke, Mario; Stefflova, Klara; Van Oosterhout, Cock; Veyrunes, Frederic; Ward, Ben; Yang, Fengtang; Yazdanifar, Golbahar; Zadissa, Amonida; Adams, David J; Brazma, Alvis; Gerstein, Mark; Paten, Benedict; Pham, Son; Keane, Thomas M; Odom, Duncan T; Flicek, Paul.

Genome Res ; 28(4): 448-459, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29563166

11.

IL-7-dependent compositional changes within the Î³Î´ T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.

Chen, Hung-Chang; Eling, Nils; Martinez-Jimenez, Celia Pilar; O'Brien, Louise McNeill; Carbonaro, Valentina; Marioni, John C; Odom, Duncan T; de la Roche, Maike.

EMBO Rep ; 20(8): e47379, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31283095

12.

Latent regulatory potential of human-specific repetitive elements.

Ward, Michelle C; Wilson, Michael D; Barbosa-Morais, Nuno L; Schmidt, Dominic; Stark, Rory; Pan, Qun; Schwalie, Petra C; Menon, Suraj; Lukk, Margus; Watt, Stephen; Thybert, David; Kutter, Claudia; Kirschner, Kristina; Flicek, Paul; Blencowe, Benjamin J; Odom, Duncan T.

Mol Cell ; 49(2): 262-72, 2013 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-23246434

13.

Functional signatures of evolutionarily young CTCF binding sites.

Azazi, Dhoyazan; Mudge, Jonathan M; Odom, Duncan T; Flicek, Paul.

BMC Biol ; 18(1): 132, 2020 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-32988407

14.

Crisflash: open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation.

Jacquin, Adrien L S; Odom, Duncan T; Lukk, Margus.

Bioinformatics ; 35(17): 3146-3147, 2019 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-30649181

15.

Evolution of transcription factor binding in metazoans - mechanisms and functional implications.

Villar, Diego; Flicek, Paul; Odom, Duncan T.

Nat Rev Genet ; 15(4): 221-33, 2014 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-24590227

16.

Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.

Chandra, Tamir; Kirschner, Kristina; Thuret, Jean-Yves; Pope, Benjamin D; Ryba, Tyrone; Newman, Scott; Ahmed, Kashif; Samarajiwa, Shamith A; Salama, Rafik; Carroll, Thomas; Stark, Rory; Janky, Rekin's; Narita, Masako; Xue, Lixiang; Chicas, Agustin; Nunez, Sabrina; Janknecht, Ralf; Hayashi-Takanaka, Yoko; Wilson, Michael D; Marshall, Aileen; Odom, Duncan T; Babu, M Madan; Bazett-Jones, David P; Tavaré, Simon; Edwards, Paul A W; Lowe, Scott W; Kimura, Hiroshi; Gilbert, David M; Narita, Masashi.

Mol Cell ; 47(2): 203-14, 2012 Jul 27.

Artigo em Inglês | MEDLINE | ID: mdl-22795131

17.

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis.

Stojic, Lovorka; Lun, Aaron T L; Mangei, Jasmin; Mascalchi, Patrice; Quarantotti, Valentina; Barr, Alexis R; Bakal, Chris; Marioni, John C; Gergely, Fanni; Odom, Duncan T.

Nucleic Acids Res ; 46(12): 5950-5966, 2018 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-29860520

18.

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.

Rudolph, Konrad L M; Schmitt, Bianca M; Villar, Diego; White, Robert J; Marioni, John C; Kutter, Claudia; Odom, Duncan T.

PLoS Genet ; 12(5): e1006024, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-27166679

19.

Mutational landscape of a chemically-induced mouse model of liver cancer.

Connor, Frances; Rayner, Tim F; Aitken, Sarah J; Feig, Christine; Lukk, Margus; Santoyo-Lopez, Javier; Odom, Duncan T.

J Hepatol ; 69(4): 840-850, 2018 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-29958939

20.

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.

Blanco, Sandra; Dietmann, Sabine; Flores, Joana V; Hussain, Shobbir; Kutter, Claudia; Humphreys, Peter; Lukk, Margus; Lombard, Patrick; Treps, Lucas; Popis, Martyna; Kellner, Stefanie; Hölter, Sabine M; Garrett, Lillian; Wurst, Wolfgang; Becker, Lore; Klopstock, Thomas; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Káradóttir, Ragnhildur T; Helm, Mark; Ule, Jernej; Gleeson, Joseph G; Odom, Duncan T; Frye, Michaela.

EMBO J ; 33(18): 2020-39, 2014 Sep 17.

Artigo em Inglês | MEDLINE | ID: mdl-25063673

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